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LIST OF ONGOING STUDIES AS ON 10th FEBRUARY, 2021

Title of the study
 
Name of the Principal Investigator
     

Pharmacokinetic drug-drug interactions between first line anti-TB and anti-diabetic drugs

  Dr. A.K. Hemanth Kumar

Pharmacokinetics of second-line anti-TB drugs in children and adolescents with MDR TB

  Dr. A.K. Hemanth Kumar

Bioavailability of fixed dose combination of first line anti-TB drugs in patients with pulmonary tuberculosis

  Dr. A.K. Hemanth Kumar

Molecular cloning and characterization of full length infectious Transmitted/Founder HIV-1 viruses

 

Dr. Luke E. Hanna

Identification of broadly neutralizing antibodies against HIV

  Dr. Luke E. Hanna

Inflammation and aging in HIV-infected individuals on long term antiretroviral therapy

  Dr. Luke E. Hanna

Identification of biomarkers that can predict progression from Latent Tuberculosis Infection to active TB disease

  Dr. Luke E. Hanna

National HIV Cohort Program Cohorts of HIV Resistance and Progression in Indian Children and Adults (CoHRPICA)

  Dr. Luke E. Hanna

Impact of malnutrition on immune responses to tuberculosis in Indian children

 

Dr. Aishwarya Venkataraman

Development and validation of a diagnostic kit for early detection of Human Papilloma Virus (HPV) infection in cervical cancer

 

Dr. N. Sudhakar

Latent  class analysis of health related quality of life of TB patients during & post treatment in a Longitudinal Design

 

Dr. M. Vasantha

Development of a Database of Clinical Study X-rays at NIRT, Chennai 

 

Dr. C. Ponnuraja

HTA for implementation of cell counters for referral of suspected dengue cases at PHC settings

 

Dr. M. Muniyandi

The Economic evaluation of standardised treatment regimens of anti-TB drugs for patients with MDR-TB (STREAM stage-II trial)

  Dr. M. Muniyandi

Social network analysis as a tool to improve active case finding at community level in Chennai

 

Dr. N. Karikalan

Measuring the socio-economic risk-benefits & health related quality of life changes associated with TB disease disclosure

  Dr. N. Karikalan

Early bactericidal activity of anti-tuberculosis drugs

  Dr.K.R. Uma Devi

Protecting and improving public health globally: Building laboratory, surveillance and workforce capacity to detect, respond to, and prevent drug resistant tuberculosis in India

  Dr.K.R. Uma Devi

Identification of the latent tuberculosis specific marker by the immunoproteomic analysis of the cell wall and membrane proteins of M. tuberculosis.

  Dr.K.R. Uma Devi

Accurate, Rapid, Robust and Economical diagnostic technologies for Tuberculosis: ARREST-TB

  Dr.K.R. Uma Devi

Crohn's disease in India: A multicenter study from a country where intestinal tuberculosis as well as Johne’s disease is endemic

  Dr.P.Kannan

Studies on epigenome wide alterations in alveolar macrophages during M. tuberculosis infections in guinea pig pulmonary tuberculosis model

  Dr.P.Kannan

Whole Genome Sequencing and Transcriptome analysis of M. tuberculosis clinical isolates from Bovine and Human Origin

  Dr.P.Kannan

Identification of Mycobacterium tuberculosis complex (MTBC) organisms in the lymph node samples of slaughtered cattle in Chennai

  Dr.P.Kannan

Dereplication guided bio-prospecting of cyclic lipopeptides from marine Bacillus sp. for inhibition of M. tuberculosis

  DR. P.Kannan

Mentor for the project ;
Dr Sagarika Devi- PI for the project

Systems biology and immunology of the effect of tuberculosis chemoprophylaxis in HIV infection

  Dr. Syed Hissar

and
Dr. Pavan Kumar

An open label, three arm, pragmatic, randomized controlled pilot study to determine the protective effect of Kabha sura kudineer (KSK)/ Nilavembu kudineer (NVK) in preventing COVID19 symptoms compared to standard Vitamin C-Zinc supplementation and to examine immune responses among healthcare workers.

  Dr. Pavan Kumar

and
Dr. Subash Babu

Identification of tuberculosis specific biomarkers in children by the Proteomic analysis of urine.

  Dr.D.Anbarasu

and
Dr. Syed Hissar

Molecular Analysis of monocyte subsets in humans infected with Mycobacterium tuberculosis

  Dr.Ramalingam B

Attenuated mycobacteria based vaccine against tuberculosis with a novel strategy for T cell priming

  Dr.K.R. Uma Devi

CRISPR mediated platform for diagnosis and rapid detection of drug resistance pattern in M. tuberculosis.

  Dr.K.R. Uma Devi

Functional characterization of oxidoreductases of M. tuberculosis

  Dr.P.Kannan

Study on Mutations Associated with Pyrazinamide Resistance in M. tuberculosis

  Dr.P.Kannan

  A cross sectional study of the systems immunology and viral diversity of SARS-CoV2 infection, COVID-19 disease and Multisystem Inflammatory Syndrome in children

 

Dr. Pavan Kumar

and
Dr. Subash Babu

Characterization and Durability of COVID-19 vaccine induced immune responses in healthcare/frontline workers

  Dr. Pavan Kumar
and
Dr. Banu Rekha

Humoral and cellular immune response among recovered COVID-19 patients: A cross-sectional study, Tiruvallur district, Chennai Corporation, Tamil Nadu, India, 2020

  Dr. Pavan Kumar (Co PI)

Role of neutralizing antibodies and inflammatory biomarkers in children with Paediatric Inflammatory Multisystem Syndrome - Temporally Associated with SARS-CoV-2 (PIMS-TS)

  Dr. Pavan Kumar (Co PI)

Regional Prospective Observational Research in Tuberculosis (RePORT) - Phase 2

  Dr. Pavan Kumar (Co PI)

CYP2R1 gene polymorphisms in pulmonary tuberculosis   

  Dr. Ramalingam B
&
Dr. Harishanker

Immunomodulation of Autophagy by Vitamin D3 in macrophages Infected with Mycobacterium tuberculosis

  Dr. Ramalingam B

Molecular and immune profiling in adults affected with COVID-19 disease

  Dr. N.Sudhakar
     

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