Planning, conduct and evaluation of controlled clinical trials.

Radhakrishna, S.

Indian Journal of Tuberculosis; 1969; 16; 42-46.

The controlled clinical trial is now a well-accepted method of measuring the relative efficacies of different therapeutic regimens for many diseases. Although its usefulness is widely appreciated, there is an insufficient awareness of the rationale and the methodology of the controlled clinical trial - that is, the reasons underlying it and the procedures involved in the execution. By taking examples from the field of pulmonary tuberculosis, the issues involved can be clearly set out.

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