Surface makers of lymphoblasts in acute lymphoblastic leukaemia.
Sarala Rajajee; Pushpa, V.; Narayanan, P.R.
Indian Journal of Haematology; 1984; 2; 234-235.
Fifty eight children with acute lymphoblastic leukaemia (ALL) were studied for the effect of initial clinical and laboratory features and surface makers of lymphoblasts on the prognosis. 18.9% of them had T-cell leukaemia while 3.4% had B-cell acute leukaemia. Six pre-treatment features were related to T-cell ALL. i.e., - age over 6 years, boys, presence of mediastinal enlargement, haemoglobin over 8 g/dl, markedly elevated leucocyte count and CNS involvement. 90% of T-cell ALL survived for less than 6 months. Both the cases of B-cell leukaemia died within 8 weeks. Identification of T and B-cell leukaemia warrants more aggressive treatment for these patients to achieve remission and survive longer.
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