Abstract

 

Tuberculosis prevalence survey in Kashmir valley.

Mayurnath, S.; Anantharaman, D.S.; Baily, G.V.J.; Radhamani, M.P.; Vallishayee, R.S.; Venkataraman, P.; Tripathy, S.P.

Indian Journal of Medical Research; 1984; 80; 129-140.

A tuberculosis survey was conducted in about 18,000 persons in Kashmir valley situated about 1650 m above the mean sea level. All persons were tested with 3 IU of PPD-S and 10 units of PPD-B. Persons aged 5 yr. and above were X-rayed (70 mm X-ray), and from such persons whose photo-fluorograms were interpreted as abnormal two specimens of sputum were collected and bacteriologically examined. In addition, a large X-ray of the chest was taken for children aged 0-4 yr. who had reaction of 10 mm or more to PPD-S. They were then clinically examined by a paediatrician, taking into account all available data, for evaluation for any evidence of tuberculosis. The results of the survey showed that the prevalence of non-specific sensitivity (59%) in the Kashmir valley is significant. The prevalence of tuberculous infection was 38 per cent. The prevalence of culture positive tuberculous patients (3 per 1000) and that of abacillary X-ray positive patients (14 per 1000) were found to be similar in the two sexes contrary to the usual experience of a higher prevalence among males. Results from studies of phage typing, susceptibility to thiophen-2-carbonic acid hydrazide (TCH) and virulence in the guinea pig of strains obtained from patients diagnosed in the survey showed that most of these strains belonged to phage type A, were resistant to TCH and were not of low virulence. Regional variations in the prevalence rates were seen, the problem of tuberculosis appeared to be more in the Baramulla district as compared to Srinagar and Anantnag districts. A comparison of results obtained from the present survey with those obtained from the BCG trial in Chingleput (Tamil Nadu) revealed that the tuberculosis situation in the two areas was quite different.

 

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