Anti-filarial IgG antibodies in patients with bancroftian filariasis and tropical eosinophilia.
Ramesh Paranjape, S.; Kumaraswami, V.; Prabhakar, R.; Subramaniam, S.; Narayanan, P.R.
Indian Journal of Experimental Biology; 1985; 23; 676-678.
Anti-filarial ( anti-B. malayi adult as well as anti-B. malayi microfilarial) IgG antibody levels were measured by enzyme linked immunosorbent assay (ELISA) in asymptomatic microfilaria carriers, acute, chronic and tropical pulmonary eosinophilia (TPE) patients, endemic and non-endemic controls. Controls from endemic areas had higher antibody titres compared with controls from non-endemic areas. The antibody response in different groups of filariasis patients was not stage specific. There were no association between clinical disease and antibody levels except in TPE. Though TPE patients had very high antibody levels, a proportion of them had low levels suggesting heterogeneity in TPE population.
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