Immunology of tuberculosis - An overview.
Rajiswami; Narayananan, P.R.
Lung India; 1985; 3; 65-68.
Over a hundred years have been passed since Robert Koch has isolated the tubercle bacillus, but still the immune mechanisms in tuberculosis are not yet completely reavelled. The information explosion in the field of immunology during the last ten years has resulted in a modest beginning in the knowledge of tuberculoimmunity at the cellular and molecular level. It is necessary to understand the host responses to Mycobacterium tuberculosis in order to appreciate the clinical consequences, diagnosis and prophylaxis of tuberculous infection. In the following sections the progress in our understanding of host's immune response to M. tuberculosis is considered with special emphasis on immunopathogenesis, immunosuppression and immunodiagnosis.
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