Multi drug resistant Tuberculosis. Multi-drug resistance in emerging and re-emerging diseases, Ed by R.C.Mahajan, Amu Therwath.

Selvakumar, N.

Indian National Science Academy (INSA), New Delhi, 2000; 133-145.          

Tuberculosis the resurgent killer, ranks first in mortality among all infectious diseases. In addition, the increased reports of `multi-drug-resistant tuberculosis' (MDR-TB) among the Human Immunodeficiency Virus (HIV) positive patients have worsen the situation. Therefore, early detection of rifampicin resistance by various methods plays a pivotal role in the management and control of MDR-TB. This article reviews the information available in this area of research.

Key words : Tuberculosis, Rifampicin resistance, DNA sequencing, PCR-SSCP, pre-rRNA, RT-PCR.

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