DDTRP – Database of drug targets for resistant pathogens.

Sundaramurthi, J.C.; Ramanandan, P.; Brindha, S.; Subashree, C.R.; Prasad, A.; Kumaraswami, V.; Hanna, L.E.

Bioinformation; 2011; 7; 98-101.       

Abstract: Emergence of drug resistance is a major threat to public health. Many pathogens have developed resistance to most of the existing antibiotics, and multidrug-resistant and extensively drug resistant strains are extremely difficult to treat. This has resulted in an urgent need for novel drugs. We describe a database called ‘Database of Drug Targets for Resistant Pathogens' (DDTRP). The database contains information on drugs with reported resistance, their respective targets, metabolic pathways involving these targets, and a list of potential alternate targets for seven pathogens. The database can be accessed freely at http://bmi.icmr.org.in/DDTRP.

Keywords : DDTRP; drug targets; resistant pathogens; database; drug discovery

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