Humoral immune response to filarial antigens in chyluria.
Alamelu Raja; Rabia Hussain; Prabhakar, R.; Narayanan, P.R.
Journal of Biosciences; 1984; 6; 723-728.
Humoral immune parameters like total immunoglobulins and specific antibody levels in serum were studied in filarial chyluria patients. Mean serum IgG was significantly reduced in this group compared to normal controls, while IgA and IgM levels remained comparable to controls. Anti-filarial antibody titre as measured by enzyme-linked immunosorbent assay also was significantly reduced. However, the total and specific IgE antibody titre was similar to that of controls. Specific IgE contents of the patients' sera could be related to their microfilaraemic status.
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