Abstract

 

Sputum examination at 2-months into continuation phase – How much does it contribute to define treatment outcome?

Thomas, A.; Chandrasekaran, V.; Santha, T.; Gopi, P.G.; Subramani, R.; Narayanan, P.R.

Indian Journal of Tuberculosis; 2006; 53; 37-39.

Summary: Objective : To assess the usefulness of sputum examination at 2-months into Continuation Phase (CP) to declare treatment outcome.

Methodology : It is a retrospective study conducted in one tuberculosis unit, Tiruvallur district of Tamilnadu among smear positive patients treated with Category I and Category II regimens from May, 1999 – December, 2003.

Results : Sputum was collected at 2-months into CP from 70% of 1551 Category I and 74% of 292 Category II patients declared cure, failed or treatment completed. Result at 2-months CP was used for giving outcome in 112 (10.3%) of 1088 Category I patients and 37 (17%) of 217 Category II patients.

Conclusion : In practice, sputum needs to be collected for 7.8% of the patients with smear positive at the end of Intensive Phase. By doing so, there will be a delay of 1 month for 3.6% of the patients in declaring ‘failure'. By deferring the sputum examination at 2 months into CP, workload of laboratory technicians can be reduced by about 30%.

eywords : Tuberculosis, treatment outcome, intensive phase and continuation phase

 

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