Staff Profile

Educational Qualification

MSc, PhD in Biochemistry

Personal Statement

I am a medical biochemist and researcher at the Indian Council of Medical Research – National Institute for Research in Tuberculosis (ICMR-NIRT), with a focus on biomarker discovery and translational research in infectious diseases. My work integrates clinical biochemistry, molecular biology, and laboratory medicine to understand disease mechanisms and improve diagnostics and patient outcomes. With training in India and international research experience, I am committed to advancing evidence-based science, strengthening laboratory quality systems, and mentoring the next generation of researchers while contributing to national efforts in tuberculosis control and public health.

Research Focus

• Intestinal barrier integrity and its role in disease pathogenesis, with focus on biomarker identification and clinical correlations.

• Biomarker discovery in tuberculosis and infectious diseases for improved diagnosis, treatment monitoring, and disease prognosis.

• Inflammation, oxidative stress, and cardiovascular risk markers in chronic diseases such as nephrotic syndrome and metabolic disorders.

• Molecular and cellular approaches in infectious disease research, including cell culture, PCR-based techniques, and biomarker assays.

• Clinical biochemistry and translational laboratory research, integrating laboratory findings with clinical outcomes to improve patient care.

Ongoing projects as Principal investigator

Assessment of Intestinal barrier integrity in Tuberculosis and its association with anti-TB drug levels

Significant Publications

1. Sreelatha S, Nagarajan U, Natarajan S. Protein targets in Mycobacterium tuberculosis and their inhibitors for therapeutic implications: A narrative review. Int J Biol Macromol. 2023 Jul15 ; 243 : 125022
2. Devang, N., Sreelatha, S. & B. V., M. Assessment of inflammatory markers and their association with disease mortality in severe COVID-19 patients of tertiary care hospital in South India. Egypt J Bronchol 16, 55 (2022).
3. Souparnika S, Nayana Devang, Aradhana Marathe. Vitamin K: A simple and efficient add on to the current treatment regime of COVID-19. Current Nutrition and Food Science. 2022 May; Volume 18, Number 7, 2022, pp. 610-617(8).
4. Naik AL, Rajan MG, Manjrekar PA, Shenoy MT, Souparnika S, Srikantiah RM, Hegde A. Effect of DOTS Treatment on Vit D Levels in Pulmonary Tuberculosis. J ClinDiagn Res. 2017 Apr;11(4):BC18-BC22.
5. Srinidhi Rai, Souparnika Sreelatha, Nayana Devang, Priyadharshini Alva, A. V. Raveendran. The Microbiota–Gut–Brain Axis and Diabetic Cognitive Impairment: A Memorable Journey. Clinical Diabetology, 2023

Awards and Honours

• University First Rank with Distinction – BSc Medical Laboratory Technology, Kerala University (2009)

• University First Rank and Two Gold Medals – MSc Medical Biochemistry, JIPMER, Puducherry (2012)

• First Prize – Poster Presentation, South Regional ACBICON (2014)

• First Prize – Oral Presentation, SOBSICON National Conference (2014)

Research Profiles